产品货号：
Z10780
中文名称：
AMPK Beta 1/PRKAB1抗体
英文名称：
Anti-AMPK Beta 1/PRKAB1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AMPK Beta 1/PRKAB1 Antibody |
| 指标别名 | AMPK;AMPK beta 1;AMPK subunit beta 1;AMPKb;HAMPKb;PRKAB1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM |
| 基因名称 | PRKAB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human AMPK beta 1 (32-68aa DRPKILMDSPEDADLFHSEEIKAPEKEEFLAWQHDLE),different from the related mouse sequence by one amino acid,and from the related rat sequence by three amino acids. |
| 实际分子量 | 38KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | 5'-AMP-activated protein kinase subunit beta-1 is an enzyme that in humans is encoded by the PRKAB1 gene.The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK).AMPK is a heterotrimer consisting of an alpha catalytic subunit,and non-catalytic beta and gamma subunits.It is an important energy-sensing enzyme that monitors cellular energy status.In response to cellular metabolic stresses,AMPK is activated,and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR),key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol.This subunit may be a positive regulator of AMPK activity.The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK.This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. |
| Uniprot ID | Q9Y478 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | protein kinase,AMP-activated,beta 1 non-catalytic subunit |
| 蛋白名全称 | 5'-AMP-activated protein kinase subunit beta-1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
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